ISSN 2586-0151 (Print)
ISSN 2586-0046 (Online)
Volume 13, Number 2 (2/2017)
Original Article <page. 141-7 >

Impact of Comorbid Obsessive Compulsive Symptoms on Quality of Life in Stable Patients with Chronic Schizophrenia

Jung Yoon Moon, MD1;Sukhoon Kang, MD1;Jung-Ho Seok, MD, PhD2,3;Chan-Hyoung Kim, MD, PhD2,3;Tae Yong Kim, MD, PhD1;Jin Hee Choi, MD1; and Hyong Seok So, MD1;

1;Department of Psychiatry, Veterans Health Service Medical Center, Seoul, 2;Departments of Psychiatry, Yonsei University College of Medicine, Seoul, 3;Institute of Behavior Science in Medicine, Yonsei University College of Medicine, Seoul, Korea

Objective : This study aimed to evaluate the relationship between comorbid obsessive compulsive disorder (OCD) and quality of life in stable patients with schizophrenia.

Methods : We interviewed 162 symptom-stable inpatients who have been on a constant dose of antipsychotics for at least 3 months prior and diagnosed as chronic schizophrenia. Subsequently, patients were classified according to the existence of OCD as evaluated using the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV). Further, all clinical and demographic data were collected and evaluated. To investigate potential interrelationships, the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Korea-Positive and Negative Symptom Scale (K-PANSS), Korean Modification of the Scale to Measure Subjective Well-Being under Neuroleptic Treatment (KmSWN) and Korean Version Quality of Life Scale (K-QOLS) were performed. Independent t-test and Chi-square test were used to compare groups and regression analysis was done to assess the relationship between the Y-BOCS and quality of life.

Results : Schizophrenia patients with OCD showed significantly earlier onset of schizophrenia, more severe psychiatric symptoms and lower quality of life, compared to those without comorbid OCD. OCD might be associated with lower quality of life in schizophrenia.

Conclusion : Schizophrenia patients with OCD showed lower quality of life than those without OCD. In the treatment for schizophrenia, evaluation of OCD might be needed to improve their quality of life and social function.


Key words : Chronic schizophrenia;Obsessive compulsive-disorder;Quality of life.

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