Case Report

대한불안의학회지 (19권2호 56-60)

A Case of a Depressed Patient With Progressive Supranuclear Palsy

우울증으로 내원한 진행성 핵상 마비 환자 1례

Seoyun Han, Jhin Goo Chang, and Su Young Lee

Department of Psychiatry, Myong-ji Hospital, Hanyang University College of Medicine, Goyang, Korea


Progressive supranuclear palsy (PSP) is rare atypical Parkinsonism accompanied by various psycho-behavioural problems. In this case report, we describe the diagnostic and treatment progress of a 65-year-old PSP patient who visited the psychiatric clinic with a depressed mood and lumbar pain resulting in a suicide attempt. Over the course of 30 months of treatment, typical characteristics of PSP, such as postural instability, dyskinesia, cognitive dysfunction and supranuclear gaze palsy, became prominent, and magnetic resonance imaging and the F-18 FP-CIT positron emission tomography revealed midbrain atrophy and reduced dopamine uptake in the basal ganglia. When treating elderly patients with depression, parkinsonism symptoms such as gait disturbances, frequent falls, tremors, and rigidity should be closely examined. (Anxiety and Mood 2023;19(2):56-60)


Depression; Progressive supranuclear palsy; Parkinsonism.