ISSN 2586-0151 (Print) | ISSN 2586-0046 (Online)
대한불안의학회지 (21권2호 35-41)
Prescription Guidelines for Benzodiazepines in International and Domestic Pharmacological Treatment of Anxiety Disorders: Focusing on Panic Disorder and Generalized Anxiety Disorder
국내외 불안장애 약물치료 지침에서의 벤조디아제핀 처방 기준: 공황장애와 범불안장애를 중심으로
Yoon Young Chang1, Eunsoo Moon2, and Won Kim1
1Department of Psychiatry, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, 2Department of Psychiatry, Pusan National University Hospital, Pusan National University College of Medicine, Pusan, Korea
Anxiety disorders, such as panic disorder and generalized anxiety disorder (GAD), can severely affect an individual’s quality of life and daily functioning. This study examines and compares both domestic and in ternational clinical guidelines regarding the prescription of benzodiazepines (BZDs) for these conditions. Al though guidelines recognize the quick anxiolytic effects of BZDs, they consistently recommend against their use as a first-line treatment due to concerns about dependence, cognitive decline, falls, and withdrawal symp toms. Instead, selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibi tors (SNRIs) are recommended as the primary treatments, with BZDs reserved for short-term adjunctive use, particularly during the initial phase of antidepressant therapy or in cases resistant to other treatments. However, clinical practice often diverges from these guidelines due to individual patient factors, the urgency of symptom relief, or issues with treatment accessibility. To enhance care and ensure safety in the use of BZDs for anxiety disorders, it is essential to continuously update national guidelines and develop patient-centered strategies that align with international standards. (Anxiety and Mood 2025;21(2):35-41)
Benzodiazepine; Panic disorder; Generalized anxiety disorder; Clinical guidelines.